环境与职业有害因素及其健康风险,主要关注于超细/纳米颗粒物的健康影响,并涉及纳米毒理学与职业工效学相关研究
1. 国家级重点项目课题,原位组装多肽纳米体系精准检测与体内代谢,2023/05-2028/04,主持。
2. 国家级重点项目,噪声与颗粒物对健康广谱影响及联合作用研究,2022/10-2025/10,主持。
3. 首都卫生发展科研专项项目,首发2022-2G-30111,北京市幼儿家庭三手烟暴露现况调查及干预研究,2022/01-2024/12,合作主持。
4. 国家自然科学基金面上项目,31971313,纳米二氧化钛对大肠癌发生发展的影响及其作用机制研究,2020/01-2023/12,主持。
5. 北京市自然科学基金面上项目,7172116,纳米二氧化钛对炎症性肠病的影响:氧化应激的作用及抗氧化剂干预研究,2017/01-2019/12,主持。
6. 国家自然科学基金青年基金项目,31400863,纳米二氧化钛致肠粘膜屏障功能损伤的机制研究,2015/01-2017/12,主持。
7. 北京市自然科学基金面上项目,7132117,纳米二氧化钛对葡萄糖吸收和代谢的影响,2013/01-2015/06,主持。
1. Shumin Duan, Hongbo Wang, Yanjun Gao, Xiang Wang, Lizhi Lyu, Yun Wang*. Oral intake of titanium dioxide nanoparticles affect the course and prognosis of ulcerative colitis in mice: involvement of the ROS-TXNIP-NLRP3 inflammasome pathway. Particle and Fibre Toxicology, 2023, 20, 24. (IF2023=7.2)
2. Lizhi Lyu, Yu Xu, Hongbo Wang, Xin Guo, Yanjun Gao, Shumin Duan, Furong Deng, Xinbiao Guo, Yun Wang*. Changes in heart rate variability of healthy subjects shortly exposed to printing shop particles and the effect of air purifier intervention. Environmental Pollution, 2022, 315, 120418. (IF2022=8.9)
3. Lizhi Lyu, Yuan Li, Xiaxian Ou, Wanqian Guo, Yi Zhang, Shumin Duan, Yanjun Gao, Yu Xu, Tianzhuo Yang, Yun Wang*. Health effects of occupational exposure to printer emissions on workers in China: Cardiopulmonary function change. NanoImpact, 2021, 21: 100289. (IF2021=6.038)
4. Yanjun Gao, Tingyu Li, Shumin Duan, Lizhi Lv, Yuan Li, Lin Xu, Yun Wang*. Impact of titanium dioxide nanoparticles on intestinal community in the 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of vitamin E. Nanoscale, 2021, 13: 1842-1862.(IF2021=8.307)
5. Yongliang Zhang, Shumin Duan, Ying Liu, Yun Wang*. The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs. Particle and Fibre Toxicology, 2021, 18, 8.(IF2021=9.112)
6. Yanjun Gao, Yixuan Ye, Jing Wang, Hao Zhang, Yao Wu, Yihui Wang, Lailai Yan, Yongliang Zhang, Shumin Duan, Lizhi Lv, Yun Wang*. Effects of titanium dioxide nanoparticles on nutrient absorption and metabolism in rats: distinguishing the susceptibility of amino acids, metal elements, and glucose. Nanotoxicology, 2020, 14(10): 1301-1323. (IF2020=5.913)
7. Sandra V. Pirela#, Kunal Bhattacharya#, Yun Wang#(co-first), Yipei Zhang, Guanghe Wang, Costas A. Christophi, John Godleski, Treye Thomas, Yong Qian, Marlene S. Orandle, Jennifer D. Sisler, Dhimiter Bello, Vincent Castranova, Philip Demokritou*. A 21-day sub-acute, whole-body inhalation exposure to printer-emitted engineered nanoparticles in rats: Exploring pulmonary and systemic effects. NanoImpact, 2019, 15: 100176. (IF2019=5.478)
8. Zhangjian Chen, Yun Wang*, Lin Zhuo, Shi Chen, Lin Zhao, Tian Chen, Yang Li, Wenxiao Zhang, Xin Gao, Ping Li, Haifang Wang, Guang Jia*. Interaction of titanium dioxide nanoparticles with glucose on young rats after oral administration. Nanomedicine: Nanotechnology, Biology and Medicine, 2015, 11(7): 1633-1642. (IF2015=5.671)
9. Yun Wang, Zhangjian Chen, Te Ba, Ji Pu, Tian Chen, Yanshuang Song, Yongen Gu, Qin Qian, Yingying Xu, Kun Xiang, Haifang Wang, Guang Jia*. Susceptibility of young and adult rats to the oral toxicity of titanium dioxide nanoparticles. Small, 2013, 9(9–10): 1742–1752. (IF2013=7.514;Highlighted by Materials Views China from Wiley;健康报2013-9-13周五第2版报道)
10. Yun Wang#, Bing Wang#, Motao Zhu, Ming Li, Huajian Wang, Meng Wang, Hong Ouyang, Zhifang Chai, Weiyue Feng*, Yuliang Zhao. Microglial activation, recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticles exposure. Toxicology Letters, 2011, 205(1): 26-37. (IF2011=3.230)