慢性病流行病学,遗传流行病学,双生子研究。
1. 国家自然科学基金面上项目,82373659,主要生活方式、DNA甲基化与血压长期变化的纵向双生子研究,2024/01-2027/12,主持;
2. 国家自然科学基金面上项目,82073633,DNA甲基化与血压因果关系的纵向双生子研究,2021/01至2024/12,主持;
3. 国家自然科学基金面上项目,81573223,以表型不一致双生子为基础的高血压DNA甲基化研究,2016/01至2019/12,主持;
4. 国家自然科学基金青年基金项目,81202264,以共同抚养和分开抚养双生子为基础的心血管疾病环境危险因素研究,2013/01至2015/12,主持;
5. 国家重点研发计划“生育健康及妇女儿童健康保障”重点专项,2023YFC2705900,双胎妊娠母胎不良结局发生机制、预测及干预策略研究,2023/12-2026/11,课题骨干;
6. 公益性行业科研专项,201502006,中国环境流行病学特殊人群队列研究,2015/09至2018/09,任务单元负责人;
7. 北京市自然科学基金青年项目,7244455,环境污染物内暴露、DNA甲基化与血脂异常关联的前瞻性队列研究,2024/01-2025/12,合作单位项目负责人;
8. 北京大学医学部教育教学研究课题,《流行病学》课程思政资源库构建研究,2021/10至2023/12,主持;
9. 北京大学公共卫生学院青年人才计划,我国双生子体质指数遗传度10余年变迁(2001-2013),2015/01至2016/12,主持;
10. 北京大学公共卫生学院青年基金,双生子相似法卵型鉴定的可靠性评价,2007/01至2007/12,主持。
1. Hong X, Miao K, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Pang Z, Yu M, Wang H, Wu X, Liu Y, Gao W*, Li L*. Association of psychological distress and DNA methylation: A 5-year longitudinal population based twin study. Psychiatry Clin Neurosci 2024;78(1):51-59.
2. Wang Y, Hong X, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Pang Z, Yu M, Wang H, Wu X, Liu Y, Gao W*, Li L*. Age effect on the shared etiology of glycemic traits and serum lipids: evidence from a Chinese twin study. J Endocrinol Invest. J Endocrinol Invest. 2024;47(3):535-546.
3. Miao K, Wang Y, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Hu R, Pang Z, Yu M, Wang H, Wu X, Liu Y, Gao W*, Li L*. Genetic and Environmental Influences on Blood Pressure and Serum Lipids Across Age-Groups. Twin Res Hum Genet 2023;26(3):223-230.
4. Hong X, Miao K, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Pang Z, Yu M, Wang H, Wu X, Liu Y, Gao W*, Li L*. Association between DNA methylation and blood pressure: A longitudinal twin study of 5-year. Hypertension 2023, 80(1): 169-181.
5. Hong X, Wu Z, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Pang Z, Cong L, Wang H, Wu X, Liu Y, Gao W*, Li L*. Longitudinal association of DNA methylation with type 2 diabetes and glycemic traits: A 5-year cross-lagged twin study. Diabetes 2022, 71(12):2804-2817.
6. Wu Z#, Chen L#, Hong X, Si J, Cao W, Yu C, Huang T, Sun D, Liao C, Pang Y, Pang Z, Cong L, Wang H, Wu X, Liu Y, Guo Y, Chen Z, Lv J, Gao W*, Li L* Temporal associations between leukocytes DNA methylation and blood lipids: A longitudinal study. Clin Epigenetics 2022, 14(1):132.
7. Zheng K, Gao W*, Cao W, Lv J, Yu C, Wang S, Huang T, Sun D, Liao C, Pang Y, Pang Z, Yu M, Wang H, Wu X, Dong Z, Wu F, Jiang G, Wang X, Liu Y, Deng J, Lu L, Li L*. Education, income, and obesity: A nationwide Chinese twin study. Obesity (Silver Spring) 2022, 30(4):931-942.
8. Wang D#, Xi Y#, Gao W*, Zheng K, Lv J, Yu C, Wang S, Huang T, Sun D, Liao C, Pang Y, Pang Z, Yu M, Wang H, Wu X, Dong Z, Wu F, Jiang G, Wang X, Liu Y, Deng J, Lu L, Cao W*, Li L. Heritability of tea drinking and its relationship with cigarette smoking in the Chinese male adult twins. Addict Biol 2022, 27(2): e13129.
9. Gao W, Lv J, Pang Y, Li L*. Role of asymptomatic and pre-symptomatic infections in covid-19 pandemic. BMJ 2021, 375:n2342.
10. Wang Z#, Peng H#, Gao W*, Cao W, Lv J, Yu C, Huang T, Sun D, Wang B, Liao C, Pang Y, Pang Z, Cong L, Wang H, Wu X, Liu Y, Li L*. Blood DNA methylation markers associated with type 2 diabetes, fasting glucose, and HbA1c levels: an epigenome-wide association study in 316 adult twin pairs. Genomics 2021: S0888-7543(21)00387-6.
(* 共同通讯作者)