Defu Ma-北京大学公共卫生学院

Faculty

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Main research directions

1. Maternal and infant health

2. Nutrition and cancer prevention

3. Nutrition prevention, intervention and risk assessment of the chronic diseases (diabetes mellitus, hypertension, hyperlipidemia and obesity).

Representative scientific research projects

Project title	Awarding organization	Year of award
The varied characteristic on the intestinal microflora and development in preterm infants	Beijing Natural Science Foundation	2016
The effect and mechanism of racemic (±)-equol and R- and S-enantiomers of equol on the proliferation, invasion and apoptosis of the lung carcinoma	National Natural Science Foundation of China	2016
The effect and mechanism of isoflavone and its metabolite equol on atherosclerosis	Beijing Natural Science Foundation	2016
The effect and mechanism of equol on the proliferation, invasion, and apoptosis of cervical cancer cells	Beijing Natural Science Foundation	2011
The effect and mechanism of equol on the proliferation, invasion, and apoptosis of colon cancer cells	Ministry of education of China	2011
The effect and mechanism of R- and S-enantiomers of equol on the colon carcinogenesis and the proliferation, invasion, and apoptosis of the colon cancer cells	National Natural Science Foundation of China	2012
The effect and mechanism of genistein on the proliferation, invasion, and apoptosis of colon cancer cells	Ministry of education of China	2013

10 representative papers

1. Wenyan Wang, Yan Xing, Yanmei Chang, Ying Wang, Yanxia You, Zekun Chen, Defu Ma f, Xiaomei Tong, Xiaohuan Guo. The impaired development of innate lymphoid cells by preterm birth is associated with the infant disease. Science Bulletin 66 (2021) 421–424. 共同通讯 IF=11.78

2. Yunli Chen; Ying Wang; Zekun Chen; Qinghua Xin; Xue Yu; Defu Ma*, The Effects of Catch-up Growth on Body Mass Index and Percent Body Fat: A Meta-analysis. Clin Nutr. 2020 Feb 27;S0261-5614(20)30094-7. IF=7.32

3. Defu Ma, Zekun Chen, Ying Wang, Xue Yu, Qinghua Xin, Yunli Chen. Effects of rapid growth on fasting insulin and insulin resistance: a system review and meta-analysis. Eur J Clin Nutr，2021 Aug;75(8):1193-1204. IF=4.016

4. Zekun Chen, Yan Xing, Xue Yu, Yuqi Dou, Defu Ma. Effect of Folic Acid Intake on Infant and Child Allergic Diseases: Systematic Review and Meta-Analysis. frontiers in pediatrics. 通讯 IF=3.418

5. Jiang M#, Gao H#, Vinyes-Pares G, Yu K, Ma DF*, Qin X, Wang P, Association between breastfeeding duration and postpartum weight retention of lactating mothers: A meta-analysis of cohort studies, Clin Nutr, 2018(37): 1224~1231. IF=7.32

6. Jiang M#, Zou Y#, Xin Q, Cai Y, Wang Y, Qin X, Ma D*. Dose-response relationship between body mass index and risks of all-cause mortality and disability among the elderly: A systematic review and meta-analysis. Clin Nutr. 2018 Jul 26. pii: S0261-5614(18)31223-8. IF=7.32

7. Defu Ma, Hiromichi Sakai, Chihiro Wakabayashi, Jong-Sook Kwon, Yoonna Lee, Shuo Liu, Qiaoqin Wan, Kumiko Sasao, Kanade Ito, Ken Nishihara, Peiyu Wang*, The prevalence and risk factor control associated with noncommunicable diseases in China, Japan, and Korea, J Epidemiol, 2017, 27(12): 568~573.

8. Ma DF, Szeto IM, Yu K, Ning Y, Li W, Wang J, Zheng Y, Zhang Y*, Wang PY*, Association between gestational weight gain according to prepregnancy body mass index and short postpartum weight retention in postpartum women, Clin Nutr, 2015, 34(2): 291~295.

9. Defu Ma, Yumei Zhang*, Yong Xue, Peiyu Wang, Titi Yang, Xianglong Shao, Isoflavone and its metabolite equol inhibit the development of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumours in ovariectomized rats, Journal of Functional Foods, 2014, 7: 580~589.

10. Ma Defu, Taku Kyoko*, Zhang Yumei*, Jia Meng, Wang Yang, Wang Peiyu, Serum lipid-improving effect of soyabean beta-conglycinin in hyperlipidaemic menopausal women, British Journal of Nutrition, 2013, 110(9):1680-1684.