Xuetao Wei

Associate Professor
weixt@263.net
Xueyuan Road 38, Haidian District, Beijing, China
Peking University

Personal profile

1992 graduated from Beijing medical university, 2008 graduated from department of nutrition and food hygiene for Ph.D.

From 1992 to 2000, in Beijing medical university worked as teaching assistant and lecturer. From 2003 till now worked as associate professor in department of toxicology, Peking University. Among this period in 2010, worked as visiting scholar in department of comparative molecular biology and pathology, John Hopkins University and from 2012-2013, worked as visiting scientist in department of immunology and microbiology, Keio University in Japan.

Currently serve as director of teaching office and deputy director of department of toxicology. Also take the position of deputy secretory general and executive manager in Chinese Environmental Mutagenesis Society, Permanent council in committee of toxicological education (Chinese society of toxicology), Permanent council in committee of immunotoxicology (Chinese society of toxicology), Committee member of GM safety committee of the Ministry of Agriculture, Committee member of national agriculture GM biosafety administrative standardization technical committees, Director of toxicological division in functional food evaluation and research center of Peking university.

Main research directions

Immunotoxicology

Molecular and cellular toxicology

Environmental pollution

Pharmaceutical toxicology

Immune modulation of bioactive agents

Safety evaluation and risk assessment

Representative scientific research projects

1. Ferritin - IL-33 related toxicity pathway in respiratory inflammation induced by aged carbon black Granted by National natural science foundation of China

2. Safety evaluation of rare-earth elements and additive in foods based on the toxic mechanism and health effect endpoint. Granted by National key research and development plan.

3. Environmental exposure and health effect of secondary particulate and ozone. Supported by Major program of National natural science foundation of China.

4. The environmental chemical behavior, ecology and toxic effect of rare-earth in agriculture. Supported by Major program of National natural science foundation of China.

5. Research of contraception methods for male--Toxicological issues of LTQ in the process of anti-fertility. Granted by National key technology support program.

6. Effect of copper excess on immune system. Granted by international copper association.

7. The role of TAK1 and TAB1 in allergy. Granted by Roche pharmaceutical Ltd.

10 representative papers

1. Jianhong Ge, Hongqian Chu, Qianqian Xiao, Weidong Hao, Jing Shang, Tong Zhu, Zhaogang Sun, Xuetao Wei*. BC and 1,4NQ-BC up-regulate the cytokines and enhance IL-33 expression in LPS pretreatment of human bronchial epithelial cells. Environ Pollut. 2021, 273:116452

2. Qianqian Xiao, Yiming Song, Hongqian Chu, Mengmeng Tang, Jianjun Jiang, Qinghe Meng, Weidong Hao, Xietao Wei*. 1,4NQ-BC enhances the lung inflammation by mediating the secretion of IL-33 which derived from macrophages. Environ Pollut. 2020, 265(Pt A):114729

3. Kang Chen1, Xuetao Wei1, Jian Zhang, Raghunath Pariyani, Johanna Jokioja, Maaria Kortesniemi, Kaisa M Linderborg, Jari Heinonen, Tuomo Sainio, Yumei Zhang, Baoru Yang. Effects of Anthocyanin Extracts from Bilberry (Vaccinium myrtillus L.) and Purple Potato (Solanum tuberosum L. var. 'Synkeä Sakari') on the Plasma Metabolomic Profile of Zucker Diabetic Fatty Rats. J Agric Food Chem. 2020, 68(35): 9436-9450.

4. Siqi Wang, Feifei Wang, Lixin Yang, Qin Li, Yao Huang, Zhiyuan Cheng, Hongqian Chu, Yiming Song, Lanqin Shang, Weidong Hao, Xuetao Wei*. Effects of coal-fired PM 2.5 on the expression levels of atherosclerosis-related proteins and the phosphorylation level of MAPK in ApoE -/- mice. BMC Pharmacol Toxicol. 2020, 21(1):34.

5. Hongqian Chu, Xi Tao, Zhaogang Sun, Weidong Hao, Xuetao Wei *. Galactooligosaccharides Protects Against DSS-induced Murine Colitis Through Regulating Intestinal Flora and Inhibiting NF-κB Pathway, Life Sciences, 2020, 242: 117220

6. Zhiyuan Cheng, Hongqian Chu, Siqi Wang, Yao Huang, Xiaohong Hou, Qi Zhang, Wenjuan Zhou, Lixia Jia, Qinghe Meng, Lanqing Shang, Yiming Song, Weidong Hao, Xuetao Wei*. TAK1 knock-down in macrophage alleviate lung inflammation induced by black carbon and aged black carbon. Environ Pollut. 2019, 253:507-515.

7. Hongqian Chu, Weidong Hao, Zhiyuan Cheng, Yao Huang, Siqi Wang, Jing Shang, Xiaohong Hou, Qinghe Meng, Qi Zhang, Lixia Jia, Wenjuan Zhou, Pengmin Wang, Guang Jia, Tong Zhu, Xuetao Wei*. Black carbon particles and ozone-oxidized black carbon particles induced lung damage in mice through an interleukin-33 dependent pathway, Science of the Total Environment, 2018, 644:217-228.

8. Zhiyuan Cheng, Jianjun Jiangb, Xiaohua Yang, Hongqian Chu, Ming Jin, Yuan Li, Xi Tao, Siqi Wang, Yao Huang, Lanqin Shang, Shuang Wu , Weidong Hao, Xuetao Wei*. The Research of Genetic Toxicity of β-phellandrene, Environmental Toxicology and Pharmacology, 2017, 54:28-33

9. Hongqian Chu, Jing Shang, Ming Jin, Yueyue Chen, Yao Pan, Yuan Li, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Qian Li, Guang Jia, Tong Zhu, Weidong Hao*, Xuetao Wei*. Comparison of lung damage in mice exposed to black carbon particles and 1,4-naphthoquinone coated black carbon particles, Science of the Total Environment, 2017, 580:572-581

10. Siqi Wang, Haifeng Jin, Qiuqing Tang, Jun Fu, Zeming Ren, Cike Peng, Lanqin Shang, Weidong Hao, Xuetao Wei*. The effect of ethephon on immune system in male offspring of mice, Environmental Toxicology and Pharmacology, 2017, 49:119-123.