Institute of Reproductive and Child Health Peking University

Aiguo Ren, Chair and Professor
The Peking University Institute of Reproductive and Child Health (IRCH) evolves from the Department of Health Care Epidemiology within the School of Public Health of the formerly Beijing Medical University. It became an independent institute in March 2000, shortly before the merger of the then Beijing Medical University and Peking University in April 2000. The mission of the institute is to improve women and children’s health through the prevention of birth defects and other adverse pregnancy outcomes. Research at IRCH focuses on the etiology of birth defects, birth defects surveillance, control and prevention; etiology and preventive measures of low birth weight, preterm birth, and perinatal death; and physiological and mental impact of Cesarean section. The institute also serves as the Key Laboratory of Reproductive Health of the Ministry of Health.

Aiguo Ren
Professor, Director of the Institute, Research interests: Nutritional, environmental, and genetic determinants of birth defects
Jianmeng Liu
Professor, Research interests: Determinants of maternal and child health, currently focusing on cesarean section, pregnancy nutrition and genetic susceptibility
Rongwei Ye
Professor, Research interests: Reproductive health epidemiology, birth defects prevention and control
Lei Jin
Associate Professor, Rearch focus: Environmental and genetic determinants of birth defects
Zhiwen Li
Associate Professor, Research interests: Environmental pollution and women and children's health
Linlin Wang
Associate Professor, Research interests: Nutritional and molecular epidemiology

Experimental Epidemiology

The institute has competed a number of projects/programs in recent years, including the China-United States Collaborative, Population-based Surveillance and Research Program for Maternal-Child and Family Health, funded by US Centers for Disease Control and Prevention, 2007-2012; The Established a Mother-Child Cohort, funded by Chinese Ministry of Science and Technology, 2009-2011; Immune Responses Caused by Environmental Exposure and Nutritional Stress as Risk Factors for Neural Tube Defects in Shanxi, China, funded by the Texas A&M Research Foundation, 2009-2010; The Demonstrational Application of An Unstructured Data Repository in Biomedical Settings, funded by the Chinese Ministry of Industry and Information Technology, 2009-2012. Currently, the mother-child cohort is on-going, with an interim target of 20,000 women. In addition, the institute is maintaining a BioBank containing a variety of biospecimens (maternal blood, cord blood, placenta, urine, skull hair, etc.) from 180,000 women, who had normal or adverse pregnancy outcomes.

Specific areas of research
>  Birth defects
>  Folate and other micronutrients in the development of birth defects
>  Polymorphisms of genes in folate pathway and birth defects
>  Environmental pollutants and birth defects
>  Nutrition, pregnancy outcomes and children’s health
>  Health impact of maternal anemia or iron deficiency
>  Supplementation with multiple vitamins and pregnancy outcomes
>  Supplementation with multiple vitamins and children’s physical and cognitive development
>  Long-term impact on children’s health of Caesarian section
>  Physical development
>  Mental and behavioral development
>  Obesity and metabolic syndrome

Location: Central Research Building in Peking University Health Science Center
Tel:+86 10 82801140
Contact Person:Pro. Aiguo Ren