任爱国

个人简介  

北京大学生育健康研究所所长、卫生部生育健康重点实验室主任、医学博士、研究员、博士生导师。
主要研究方向为出生缺陷和先天残疾的预防和控制。
曾承担国家科技攻关计划课题和国家自然科学基金课题,并为两项“国家重点基础研究发展规划(973)”课题学术骨干。
现为国家自然科学基金课题负责人、美国NIH课题共同负责人。
对我国某些地区神经管缺陷高发的原因进行了系统调查和研究,提出了燃煤导致的空气污染可能与胎儿神经管缺陷发病有关的假设并进行了初步验证。
独立或合作发表科研论文120余篇,其中SCI论文40余篇。
中国妇幼保健协会理事、《中国生育健康杂志》主编、4种国际学术期刊常务编委或编委、10余种国际期刊审稿人。

研究领域

出生缺陷的预防和控制,包括出生缺陷的环境和遗传病因,以及出生缺陷的干预措施

不孕不育症流行病学

孕产妇营养与不良妊娠结局

科研项目

出生缺陷高发区的病因和综合防治措施的研究。编号:2002BA709B11。执行期限:2002~2004。角色:课题负责人。资助来源:科技部。

多环芳烃及其代谢酶基因多态性与胎儿神经管畸形发生危险性之间的关系。编号:31071315。执行期限:2011~2013。角色:课题负责人。资助来源:国家自然科学基金委员会。

多环芳烃致胎儿神经管缺陷作用及氧化应激机制研究。编号:31371523。执行期限:2014~2016。角色:课题负责人。资助来源:国家自然科学基金委员会。

Study of Neural Tube Defects Etiology: Genome and Exposome. Grant number: 1R01ES021006-01A1. Role: Project period: 08/16/2012 – 06/30/2015. Co-Principal Investigator. Funding agency: National Institutes of Health, USA.

China-US Collaborative Program for Maternal-Child and Family Health. Grant number: 5U01DD000293. Project period: 06/01/2007 – 05/31/2012. Role: Senior investigator and Program coordinator. Funding agency: US Centers for Disease Control and Prevention.

代表性论文(*通讯作者)

1. Yuan Y, Jin L, Wang L, Li Z, Zhang L, Zhu H, Finnell RH, Zhou G, Ren A*. Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population. Reprod Toxicol, 2013,37:70-75.

2. Liu J, Jin L, Zhang L, Li Z, Wang L, Ye R, Zhang Y, Ren A*. Placental concentrations of manganese and the risk of fetal neural tube defects. J Trace Elem Med Biol, 2013,10.1016/j.jtemb.2013.04.001(0).

3. Li Z, Zhang L, Ye R, Liu J, Pei L, Zheng X, Ren A*. Partner cigarette smoking and risk of neural tube defects among infants of non-smoking women in northern China. Tob Control, 2013, http://dx.doi.org/10.1136/tobaccocontrol-2011-050384.

4. Jin L, Zhang L, Li Z, Liu JM, Ye R, Ren A*. Placental concentrations of mercury, lead, cadmium, and arsenic and the risk of neural tube defects in a Chinese population. Reprod Toxicol, 2013,35(1):25-31.

5. Ma J, Qiu XH, Ren AG*, Jin L, Zhu T. Using placenta to evaluate the polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) exposure of fetus in a region with high prevalence of neural tube defects. Ecotoxicol Environ Saf, 2012,86:141-146.

6. Ye R, Ren A, Zhang L, Li Z, Liu J, Pei L, Zheng X. Tea drinking as a risk factor for neural tube defects in northern China. Epidemiology, 2011,22(4):491-496.

7. Ren A*, Qiu X, Jin L, Ma J, Li Z, Zhang L, Zhu H, Finnell RH, Zhu T*. Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proc Natl Acad Sci U S A, 2011,108(31):12770-12775.

8. Li Z, Zhang L, Ye R, Pei L, Liu J, Zheng X, Ren A*. Indoor air pollution from coal combustion and the risk of neural tube defects in a rural population in shanxi province, China. Am J Epidemiol, 2011,174(4):451-458.

9. Li Z, Liu J, Ye R, Zhang L, Zheng X, Ren A*. Maternal passive smoking and risk of cleft lip with or without cleft palate. Epidemiology, 2010,21(2):240-242.

10. Pei L, Liu J, Zhang Y, Zhu H, Ren A*. Association of reduced folate carrier gene polymorphism and maternal folic acid use with neural tube defects. Am J Med Genet B Neuropsychiatr Genet, 2009,150B(6):874-878.